In the face of rapid technological evolution, traditional automotive business models are being disrupted, demanding new approaches to competitiveness in the global market. The European Space Agency’s Directorate of Connectivity and Secure Communications and its Space for 5G/6G Programme Office are at the forefront of driving this transformation, collaborating with leading automotive partners to revolutionise mobility through space-based technologies. By fostering innovation in connected and autonomous vehicles, the European Space Agency (ESA) is unlocking new possibilities in smart transportation, laying the foundation for the future of mobility that integrates vehicles, infrastructure, and users in a seamless communication network.