Under NASA’s Artemis Program, NASA plans to collaborate with commercial and international partners to establish a long-term human and robotic presence on the Moon. Critical lunar infrastructure includes having a robust surface wireless communications and navigation network to be developed over time by many organizations, public and private. NASA’s Space Technology Mission Directorate (STMD) has envisioned a lunar surface future that includes the use of 3rd Generation Partnership Project (3GPP) cellular and 802.11 Wi-Fi technologies. NASA and Nokia Bell Labs are studying and validating the benefits and trade-offs of using 3GPP 4G and 5G technologies originally developed for use here on Earth, and how 3GPP technologies and 802.11 Wi-Fi technologies can be integrated to provide a robust and resilient end-to-end network architecture and solution design. Furthermore, as the 3GPP organization defines future 6G capabilities, NASA wants to understand how that could enhance lunar science and exploration missions and commercial endeavours to provide even more advanced, scalable and high-performance connectivity solutions.